The Saudi Rare Disease Summit is a unique platform that explores the area of rare diseases and fosters collaboration among diverse stakeholders, such as researchers, clinicians, caregivers, and policymakers for optimizing patients’ care. The program aims to cover a wide range of topics related to rare diseases, from cutting-edge research to patient-centric approach, as well as novel therapies and treatments. The summit creates a friendly environment for engaging and empowering rare disease multidisciplinary teams, highlighting the importance of their perspective in rare diseases research and care, and emphasizing on the importance of a holistic approach to rare disease management.